Norovirus Prevention
Join a research study testing prevention of Norovirus, an investigational vaccine designed to help prevent norovirus illness in adults 60 and older.
60+
About 13 months
3-4 clinic visits plus 6–7 phone call visits
About This Study
Norovirus — often called the stomach flu or stomach bug — causes sudden nausea, vomiting, and diarrhea. Right now, there is no approved vaccine to prevent it. This study is testing an investigational vaccine called mRNA-1403 to see if it is safe and if it can help prevent norovirus illness in adults.
If you join, you will be randomly assigned (like a coin flip) to receive either the vaccine or a placebo — a shot that looks the same but contains no active vaccine. Neither you nor the study doctor will know which one you received. You will receive one injection in your arm on the first day of the study.
Taking part involves clinic visits and phone check-ins over the course of the study. You will also use a simple electronic diary (eDiary) on your phone to track any symptoms. If you develop stomach-bug symptoms during the study, the team will check in with you daily until you feel better and may ask you to collect a stool sample at home. Your safety and health will be monitored throughout the entire study. You are never directly exposed to the norovirus or any virus during the study.
You May Qualify If You
- You are 60 years of age or older
- You are able to attend scheduled visits and follow-up phone calls
- You are generally healthy or have stable, well-controlled medical conditions
- You have not had stomach-bug symptoms or close contact with someone who did in the last 14 days before joining
- You have not received an investigational treatment in another clinical trial within the last 90 days
- You do not have a history of Guillain-Barré syndrome
Interested in This Study?
Contact us to learn more and see if you qualify.