RecruitingKnee Arthritis with Cartilage Damage

Knee Arthritis

An investigational study comparing surgically applied stem cells vs standard of care debridement when treating damaged cartilage in the knee. (All MRI and surgery costs are fully covered by the study)

Age Range

18-75

Duration

About 27 months (a little over 2 years)

Visits

At least 10 visits

Compensation

Up to $1,215 total

About This Study

This study is looking at a new treatment called CARTISTEM®, which is made from stem cells found in umbilical cord blood. Researchers want to find out if CARTISTEM® can help reduce knee pain and improve knee function in people with knee arthritis and cartilage damage. CARTISTEM® will be compared to a standard surgical procedure called debridement, which removes damaged cartilage.

If you join, you will be randomly assigned, to receive either debridement alone or debridement plus CARTISTEM®. You will have a 50% chance of receiving each treatment. Neither you nor the study evaluator will know which treatment you received. After surgery, you will follow a rehabilitation program and return for follow-up visits over 2 years.

You will have at least 10 study visits in total: a screening visit, a baseline visit, a surgery visit, and 7 follow-up visits at 2 weeks and 3, 6, 9, 12, 18, and 24 months after surgery. All study-related tests and procedures are provided at no cost to you, and you will receive payment for each visit you complete.

You May Qualify If You

  • You are between 18 and 75 years old
  • You have been diagnosed with knee osteoarthritis
  • You have tried conservative knee treatments (such as physical therapy, injections, or pain medications) for at least 3 months without enough relief
  • Your body mass index (BMI) is 35 or below
  • You are able to follow a rehabilitation program after surgery
  • You are willing to attend follow-up visits for up to 2 years after surgery

Interested in This Study?

Contact us to learn more and see if you qualify.

Have Questions?

Our team is available to answer your questions about this study.

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