Knee Surgery

This study compares surgically applied Stem Cells versus standard of care debridement when treating damaged cartilage in the knee. (All MRI and surgery costs are fully covered by the study)

At a glance

Condition: Knee Surgery
Enrollment status: Recruiting
Age range: 18-75
Study duration: About 27 months (a little over 2 years)
Visits: At least 10 visits
Participant compensation: Up to $1,215 total

Referral criteria summary

You are between 18 and 75 years old
You have been diagnosed with knee osteoarthritis
You have tried conservative knee treatments (such as physical therapy, injections, or pain medications) for at least 3 months without enough relief
Your body mass index (BMI) is 35 or below
You are able to follow a rehabilitation program after surgery
You are willing to attend follow-up visits for up to 2 years after surgery

This is the study's public summary, not its full inclusion and exclusion criteria. A patient who does not obviously fit may still qualify — and the reverse is also true. Call the clinician line to talk through a specific patient before ruling them in or out.

About this study

This study is looking at a new Stem Cell treatment, which is made from stem cells found in umbilical cord blood. Researchers want to find out if the medication can help reduce knee pain and improve knee function in people with knee arthritis and cartilage damage. The medication will be compared to a standard surgical procedure called debridement, which removes damaged cartilage.

If you join, you will be randomly assigned, to receive either debridement alone or debridement plus the study medication. You will have a 50% chance of receiving each treatment. Neither you nor the study evaluator will know which treatment you received. After surgery, you will follow a rehabilitation program and return for follow-up visits over 2 years.

You will have at least 10 study visits in total: a screening visit, a baseline visit, a surgery visit, and 7 follow-up visits at 2 weeks and 3, 6, 9, 12, 18, and 24 months after surgery. All study-related tests and procedures are provided at no cost to you, and you will receive payment for each visit you complete.

How to refer a patient

Fax the referral form — call (252) 515-0050 to confirm the current referral fax number. The form is at westclinicalresearch.com/providers/referral-form
Call (252) 515-0050 — ask for the clinical research team. Mon-Fri 8:00 AM – 4:00 PM.
Patients calling for themselves should use (252) 659-5222, which reaches the recruitment team.

A coordinator calls your office to confirm a referral before the patient is contacted.